Zbigniew Darzynkiewicz, M.D., Ph.D.


 

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     About Zbigniew 
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    Book Chapters:

    1968

    1. Darzynkiewicz, Z.: Cell Biology. In: The Human Being ("Czlowiek"). Darzynkiewicz et al. (eds.), Wiedza Powszechna, Warsaw, pp. 1-98, 1968 (in Polish).

    1970

    2. Darzynkiewicz, Z.: Histochemistry and Cytochemistry. In: Textbook of Cell Biology. Ostrowski, K. et al., (eds.), School of Medicine in Warsaw (Publ.), pp 115-160, 1970 (in Polish).

    3. Darzynkiewicz, Z.: The Genetic Code. In: Textbook of Cell Biology. Ostrowski, K. et al., (eds). School of Medicine in Warsaw (Publ.) pp 195-265, 1970 (in Polish).

    1976

    4. Darzynkiewicz, Z.: Simultaneous quantitation of DNA and RNA in situ. In: PROTOCOLS, Protocol 21, 12/76, Bio/Physics Systems, Inc., Mahopac, New York, pp. 1-4, 1976.

    1978

    5. Darzynkiewicz, Z.: Discrimination of G0, G1, S, G2 and M phases by cytofluorographic analysis. In: PROTOCOLS, Protocol 25, Ortho Instruments, Weston, MA, pp. 1-5, 1978.

    1979

    6. Darzynkiewicz, Z.: Drug Effects on Cell Cycle: A discussion. In: Effects of Drugs on Cell Nucleus. Bush, H. et al. (Eds.), Academic Press, New York, NY, pp. 470-474, 1979.

    7. Darzynkiewicz, Z.: Acridine Orange as a Molecular Probe in Studies of Nucleic Acids In Situ. In: Flow Cytometry and Sorting. Melamed, M.R., Mendelsohn, M. and Mullaney, P. (eds.), John Wiley and Sons, New York, pp. 285-316, 1979.

    1981

    8. Melamed, M.R., and Darzynkiewicz, Z.: Acridine Orange as a Quantitative Cytochemical Probe to Flow Cytometry. In: The Widening Horizons of Histochemistry. Polak, M.J. and Stoward, P.J. (eds.), John Wiley and Sons, New York, pp. 237 261, 1981.

    1982

    9. Darzynkiewicz, Z., and Traganos, F.: RNA Content and Chromatin Structure in Cycling and Non-cycling Cell Populations Studied by Flow Cytometry. In: The Genetic Expression in the Cell Cycle, Vol. 1. McCarthy, K.S., Sr. and Padilla, G.M. (eds.), Academic Press, New York, pp. 103-128, 1982.

    1984

    10. Darzynkiewicz, Z.: Metabolic and kinetic compartments of the cell cycle distinguished by multiparameter flow cytome try. In: Growth, Cancer and the Cell Cycle. Skehan, P. and Friedman, S.I. (eds.), Humana Press, Clifton, New Jersey, pp. 249-278, 1984.

    1986

    11. Darzynkiewicz, Z., Traganos, F., and Kimmel, M.: Assay of Cell Cycle Kinetics by Multivariate Flow Cytometry. In: Techniques of Cell Cycle Analysis. Gray, J.W. and Darzynkiewicz, Z. (eds.), Humana Press, Inc., Clifton, New Jersey, pp. 291-332, 1986.

    12. Darzynkiewicz, Z.: Cytochemical Probes of Cycling and Quiescent Cells Applicable for Flow Cytometry. In: Techniques of Cell Cycle Analysis. Gray, J.W. and Darzynkiewicz, Z., (eds.), Humana Press, Inc., Clifton, New Jersey, pp. 225-279, 1986.

    1990

    13. Darzynkiewicz, Z.: Probing Nuclear Chromatin by Flow Cytometry. In: Flow Cytometry and Sorting. Melamed, M.R., Mendelsohn, M. and Lindmo, T. (eds.), Alan R. Liss, Inc., New York. 1990, pp. 315-340.

    14. Darzynkiewicz, Z., and Traganos, F.: Multiparameter Flow Cytometry in Studies of the Cell Cycle. In: Flow Cytometry and Sorting. Melamed, M.R., Mendelsohn, M. and Lindmo, T. (eds.), Alan R. Liss, Inc., New York. 1990, pp. 469-502.

    15. Darzynkiewicz, Z., and Kapuscinski, J.: Acridine Orange, a Versatile Probe of Nucleic Acids and Other Cell Constituents. In: Flow Cytometry and Sorting. Melamed, M.R., Mendelsohn, M. and Lindmo, T. (eds.), Alan R. Liss, Inc., New York. 1990, pp. 291-314.

    16. Darzynkiewicz, Z. and Crissman, H.A.: Preface. In: Methods in Cell Biology, Vol. 33. Flow Cytometry. Z. Darzynkiewicz and H.A. Crissman, (eds.), Academic Press, New York, N.Y. 1990, pp, xv-xvii.

    17. Darzynkiewicz, Z.: Acid-Induced Denaturation of DNA in situ as a Probe of Chromatin Structure. In: Methods in Cell Biology, Vol. 33. Flow Cytometry. Z. Darzynkiewicz and H.A. Crissman, (eds.), Academic Press, New York, N.Y. 1990, pp. 337-352.

    18. Darzynkiewicz, Z.: Differential Staining of DNA and RNA in Intact Cells and Isolated Cell Nuclei with Acridine Orange. In: Methods in Cell Biology. Vol. 33. Flow Cytometry. Z. Darzynkiewicz and H.A.Crissman, (eds.), Academic Press, New York, N.Y. 1990, pp. 285-298.

    19. Kapuscinski, J. and Darzynkiewicz, Z.: Spectral Properties of Fluorochromes Commonly Used in Flow Cytometry. In: Methods in Cell Biology, Vol. 33. Flow Cytometry. Z. Darzynkiewicz and H.A. Crissman, (eds.), Academic Press, New York, N.Y. 1990 pp., 655-669.

    20. Crissman, H.A., Darzynkiewicz, Z., Steinkamp, J.A. and Tobey, R.A.: Simultaneous Fluorescent Labeling of DNA, RNA and Protein. In: Methods in Cell Biology. Vol. 33. Flow Cytometry. Z. Darzynkiewicz and H.A.Crissman, (eds.), Academic Press New York, N.Y. 1990, pp. 305-314.

    1991

    21 Darzynkiewicz, Z.: Multiparameter Analysis of The Cell Cycle by Flow Cytometry: Clinical Implications. In: Proc. Int. Symp. Flow Cytometry and Image Analysis for Clinical Applications. June 30-July 3, 1991, Elsevier, Amsterdam pp. 311-318.

    22. Darzynkiewicz, Z., Traganos, F., Kimmel, M., and Myc, A.: Kinetic and Metabolic Heterogeneity of Cells in the Cell Cycle. In: Stochastic Modelling in Biology. P. Tautu, (ed.), World Scientific Publishing, Singapore 1991, pp. 30-50.

    23. Darzynkiewicz, Z.: Flow Cytometric Methods for RNA Content Analysis. In: Methods: A Companion to Methods in Enzymology. E. Rothenberg, (ed.) Academic Press, New York. 2:200-206, 1991.

    1992

    24. Darzynkiewicz, Z.: Mammalian Cell Cycle Analysis. In: The Cell Cycle: A Practical Approach. P. Fantes and R. Brooks (eds.), Oxford University Press, Oxford, 1992, pp. 45-68.

    1993

    25. Darzynkiewicz, Z.: The Cell Cycle. Application of Flow Cytometry in Studies of Cell Reproduction. In: Flow Cytometry: Principles and Clinical Applications. K.D. Bauer, R.E. Duque & T.V. Shankey, (eds.), Williams & Wilkins, Baltimore, MD, pp. 13-40, 1993.

    26. Darzynkiewicz, Z.: Chromatin Structure Determination in situ Using AO. In: Handbook of Flow Cytometry Methods, J.P. Robinson, Z. Darzynkiewicz, P. Dean, L. Dressler, H. Tanke and L. Wheeless (eds.), Wiley-Liss, New York, N.Y. 1993, p. 113-114

    27. Darzynkiewicz, Z.: DNA-RNA Differential Staining Using AO. In: Handbook of Flow Cytometry Methods, J.P. Robinson, Z. Darzynkiewicz, P. Dean, L. Dressler, H. Tanke and L. Wheeless (eds.), Wiley-Liss, New York, N.Y. 1993, p. 114-115.

    28. Darzynkiewicz, Z.: DNA Content Analysis Using DAPI DNA/Protein Staining Using a Combination of DAPI and Sulforhodamine 101. In: Handbook of Flow Cytometry Methods, J.P. Robinson, Z. Darzynkiewicz, P. Dean, L. Dressler, H. Tanke and L. Wheeless (eds.), Wiley-Liss, New York, N.Y. 1993, pp. 116-117.

    29. Darzynkiewicz, Z.: Detection of DNA Strand Breaks Associated with Apoptosis. In: Handbook of Flow Cytometry Methods, J.P. Robinson, Z. Darzynkiewicz, P. Dean, L. Dressler, H. Tanke and L. Wheeless (eds.), Wiley-Liss, New York, N.Y. 1993, pp. 206-207.

    30. Darzynkiewicz, Z., Gorczyca, W., Hotz, M.A., Lassota, P., Bruno, S., and Traganos, F.: Chromatin Changes Accompanying Apoptosis Detected by Flow Cytometry. In: Flow Cytometry: New Developments. A. Jacquemin-Sablon, (ed.), Springer-Verlag, Paris; NATO ASI Series, 1993, pp. 311-326.

    31. Darzynkiewicz, Z., Gorczyca, W., Lassota, P. and Traganos, F.: Altered sensitivity of DNA in situ to denaturation in apoptotic cells. In: Clinical Flow Cytometry, A.L. Landay, K.A.Ault, K.D.Bauer and P.S. Rabinovitch, eds. Ann. N.Y.Acad. Sci. Vol. 677. N.Y. Ac. Sci., New York, 1993. pp 334-340. 1994

    32. Darzynkiewicz, Z.: Cell Cycle Analysis by Flow Cytometry. In: Handbook of Cell Biology, J. Celis (ed.) Academic Press, 1994, pp 261-271.

    33. Darzynkiewicz, Z., Robinson, J.P., and Crissman, H.A. Preface to the Second Edition. In: Methods in Cell Biology Flow Cytometry (2nd edition). Z. Darzynkiewicz, J.P. Robinson, and H.A. Crissman (eds.), Academic Press, New York, N.Y. 1994, pp. xv-xvii

    34. Darzynkiewicz, Z.: Assays of Cell Viability. Discrimination of Cells Dying by Apoptosis. In: Methods in Cell Biology Flow Cytometry (2nd edition). Z. Darzynkiewicz, J.P. Robinson and H.A. Crissman (eds.), Academic Press, New York, N.Y. 1994, pp. 15-38.

    35. Darzynkiewicz, Z.: Acid-Induced Denaturation of DNA in Situ as a Probe of Chromatin Structure. In: Methods in Cell Biology Flow Cytometry (2nd edition). Z. Darzynkiewicz, J.P. Robinson, and H.A. Crissman (eds.), Academic Press, New York, N.Y. 1994, pp. 527-542.

    36. Darzynkiewicz, Z.: Simultaneous Analysis of Cellular RNA and DNA Content. In: Methods in Cell Biology Flow Cytometry (2nd edition). Z. Darzynkiewicz, J.P. Robinson and H.A. Crissman (eds.), Academic Press, New York, N.Y. 1994, pp. 401-420.

    37. Traganos, F., and Darzynkiewicz, Z.: Lysosomal Proton Pump Activity: Supravital Cell Staining with Acridine Orange Differentiates Leukocyte Subpopulations. In: Methods in Cell Biology Flow Cytometry (2nd edition). Z. Darzynkiewicz, J.P. Robinson and H.A. Crissman (eds.), Academic Press, New York, N.Y. 1994, pp. 185-194.

    38. Darzynkiewicz, Z., Traganos, F. and Gong: Analysis of DNA content and cyclin protein expression in studies of DNA ploidy, growth fraction, lymphocyte stimulation and the cell cycle. In: Methods in Cell Biology Flow Cytometry (2nd edition). Z. Darzynkiewicz, J.P. Robinson and H.A. Crissman (eds.), Academic Press, New York, N.Y. 1994, pp. 421-436.

    1995

    39. Darzynkiewicz, Z., Li, X., Gong, J., Hara, S., and Traganos, F.: Analysis of Cell Death by Flow Cytometry. In: Cell Growth and Apoptosis. A practical Approach. 2nd edition. G. Studzinski, Ed., Oxford University Press, Oxford, England, 143-168, 1995

    40 Darzynkiewicz, Z.: Analysis of cell death by flow cytometry. In: Flow Cytometry: New Developments. A. Jacquemin-Sablon, (ed.), Springer-Verlag, Paris; NATO ASI Series, Vol. 95. pp. 115 - 130, 1995.

    41 Darzynkiewicz, Z. Practical Flow Cytometry (3rd Edn) by Howard M. Shapiro, Wiley-Liss, 1995 ISBN 0471 303763 Trends Cell Biol., 5: 373-374, 1995.

    1996

    42. Darzynkiewicz, Z.: Detection of Apoptosis by Flow Cytometry. In. "Educational Program of the 26th Congress of the International Society of Hematology". Singapore, 2 - 29 Aug, 1996.

    43. Darzynkiewicz, Z. and Li, X.: Meaurements of cell death by flow cytometry. In: Techniques in Apoptosis: A users' guide. T.G. Cotter and S.J. Martin, Eds. Portland Press, London, pp. 71 - 106. 1996.

    44. Melamed, M.R. and Darzynkiewicz, Z.: Flow cytometry in cytopathology. In: Comprehensive Cytopathology. Second Edition. M. Bibbo, Ed. W.B. Saunders, Philadelphia, PA, pp. 1023-1032, 1996.

    1997

    45. Darzynkiewicz, Z., Li, X., Gong, J., and Traganos, F.: Methods for analysis of apoptosis by flow cytometry. In: Manual of Clinical Laboratory Immunology. 5th Edition, ASM Press, Washington, DC. 334-343, 1997

    46. Darzynkiewicz, Z. Nucleic Acid Analysis. Introduction. In: Current Protocols in Cytometry. P. Robinson, Z. Darzynkiewicz, P. Dean, L. Dressler, P. Rabinovitch, C. Stewart, H. Tanke and L. Wheeless, Eds. Current Protocols/Wiley-Liss, New York, N.Y. 1997; 7.0.1 -7.0.2.

    47. Darzynkiewicz, Z., and Juan, G.: Introduction and Overview of Nucleic Acid Analysis. In: Current Protocols in Cytometry. P. Robinson, Z. Darzynkiewicz, P. Dean, L. Dressler, P. Rabinovitch, C. Stewart, H. Tanke and L. Wheeless, Eds. Current Protocols/Wiley-Liss, New York, N.Y. 1997; 7.1.1 -7.1.4.

    48. Darzynkiewicz, Z., and Juan, G.: Section 7. 7: Differential staining of DNA and RNA. In: Current Protocols in Cytometry. P. Robinson, Z. Darzynkiewicz, P. Dean, L. Dressler, P. Rabinovitch, C. Stewart, H. Tanke and L. Wheeless, Eds. Current Protocols/Wiley-Liss, New York, N.Y. 1997; 7.3.1 - 7.3.13.

    49. Darzynkiewicz, Z., and Juan, G.: Section 7. 6: Analysis of DNA content and DNA strand breaks for detection of apoptotic cells. In: Current Protocols in Cytometry. P. Robinson, Z. Darzynkiewicz, P. Dean, A. Orfao, P. Rabinovitch, C. Stewart, H. Tanke and L. Wheeless, Eds. Current Protocols/Wiley-Liss, New York, N.Y. 1997; 7.4.1 - 7.4.8.

    50. Darzynkiewicz, Z., and Juan, G.: Section 7. 2: DNA content measurement for DNA ploidy and cell cycle analysis. In: Current Protocols in Cytometry. P. Robinson, Z. Darzynkiewicz, P. Dean, A. Orfao, P. Rabinovitch, C. Stewart, H. Tanke and L. Wheeless, Eds. Current Protocols/Wiley-Liss, New York, N.Y. 1997; pp. 7.5.1 - 7.5.24

    51. Darzynkiewicz, Z: Methods in analysis of apoptosis and necrosis. In: Advaced Methodologies in Flow Cytometry. Andrea Cossarizza, Ed. Universita Degli Studi di Modena, Modena, Italy. 1997. pp 9-34.

    1998

    52. Darzynkiewicz, Z., and Juan, G.: Section 7. 8: Analysis of DNA denaturation. In: Current Protocols in Cytometry. P. Robinson, Z. Darzynkiewicz, P. Dean, A. Orfao, P. Rabinovitch, C. Stewart, H. Tanke and L. Wheeless, Eds. Current Protocols/Wiley-Liss, New York, N.Y. 1998. pp. 7.8.1-7.8.4.

    53. Darzynkiewicz, Z., and Juan, G.: Section 7. 7. Analysis of DNA content and BrdUrd incorporation. In: Current Protocols in Cytometry. P. Robinson, Z. Darzynkiewicz, P. Dean, A. Orfao, P. Rabinovitch, C. Stewart, H. Tanke and L. Wheeless, Eds. Current Protocols/Wiley-Liss, New York, N.Y.1998. pp. 7.7.1 - 7.7.6.

    54. Juan, G., and Darzynkiewicz, Z.: Section 7. 9. Bivariate analysis of DNA content and expression of cyclin proteins. In: Current Protocols in Cytometry. P. Robinson, Z. Darzynkiewicz, P. Dean, A. Orfao, P. Rabinovitch, C. Stewart, H. Tanke and L. Wheeless, Eds. Current Protocols/Wiley-Liss, New York, N.Y.1998. pp. 7.9.1 - 7.9.4.

    55. Juan, G. and Darzynkiewicz, Z.: Cell Cycle Analysis by Flow Cytometry. In: Handbook of Cell Biology, 2nd Edition, J. Celis (ed.) Academic Press, 1998. pp. 261-274.

    56. Juan, G. and Darzynkiewicz, Z.: In situ DNA strand break labeling for the analysis of apoptosis and cell proliferation. In: Handbook of Cell Biology, 2nd Edition, J. Celis (ed.) Academic Press, 1998. pp 341-350.

    57. Mazur L., and Darzynkiewicz, Z.: Apoptosis in hematopoetic system. In: Blood Physiology: Selected Topics. Z. Dabrowski, Ed., "Wydawnictwo Naukowe PWN", Warsaw, Poland, (in Polish),1998; pp. 286-315 .

    58. Juan, G., and Darzynkiewicz, Z.: Detection of cyclins in individual cells by flow and laser scanning cytometry. In.: Methods in Molecular Biology Vol. 91. Flow Cytometry Protocols. M.J.. Jaroszeski and R. Heller, Eds. Humana Press, Totowa, N.J. 1998, pp. 67-75.

    59. Gorczyca, W. and Darzynkiewicz, Z.: Analysis of apoptosis by flow cytometry. In: Methods in Molecular Biology. Vol. 91. Flow Cytometry Protocols. M.J. Jaroszeski and R. Heller, Eds. Humana Press, Totowa, N.J. 1998, pp 217-238.

    60. Darzynkiewicz, Z., and Traganos, F.: Measurement of apoptosis. In: Advances in Biochemical Engineering/Biotechnology. Apoptosis. Mohamed Al-Rubeai, Ed. 1998, pp 33-73.

    61. Darzynkiewicz, Z., Bedner, E., Burfeind, P., and Traganos, F.: Analysis of apoptosis by flow and laser scanning cytometry. In: Apoptosis. Detection and Assay Methods. Biotechniques Series on Molecular Laboratory Methods, No. 2. L. Zhu and G. Zhang, Eds. BioTechiques Books (Division of Eaton Publishing) Palo Alto, CA., 1998. pp. 75-92.

    1999

    62. Darzynkiewicz, Z., X. Li and Bedner, E: Detection of DNA strand breakage in analysis of apoptosis and cell proliferation by flow and laser scanning cytometry. In: Methods in Molecular Biology. Vol 113, "DNA Repair Protocols: Eukaryotic Systems". D.S. Henderson, Ed. Humana Press., Inc., Totowa, N.J. 1999, pp 607-619.

    63. Darzynkiewicz, Z. and Juan, G., Selective extraction of fragmented DNA from apoptotic cells for analysis by gel electrophoresis and identification of apoptotic cells by flow cytometry. In: Methods in Molecular Biology. Vol. 113, "DNA Repair Protocols: Eukaryotic systems". D.S. Henderson, Ed. Humana Press., Totowa, N.J. 1999, pp. 599-606.

    64. Darzynkiewicz, Z, Bedner, E. and Li, X.: Analysis of cell death by flow- and laser scanning- cytometry. In: Apoptosis: A Practical Approach. Ed. by G. Studzinski. Oxford University Press, Oxford, UK. 1999, pp. 57-80

    65 Juan, G., Traganos, F. and Darzynkiewicz, Z.: Cytometry of the pRB pathway. In: Cell Cycle: A Practical Approach. Ed. by G. Studzinski, Oxford University Press, Oxford, UK. 1999, pp. 145-159.

    2000

    66. Darzynkiewicz, Z., Juan, G. and Bedner, E.: Determining cell cycle stages by flow cytometry. In: Current Protocols in Cell Biology. JS Bonifacino, M. Dasso, J. Harford, J Lippincott-Schwartz and KM Yamada, Eds. Current Protocols. Wiley-Liss, New York, NY, 2000, pp. 8.4.1-8.4.18,

    67. Darzynkiewicz, Z and Bedner E.: Analysis of apoptotic cells by flow- and laser scanning- cytometry. In Methods in Enzymology, Vol 322: Methods in Apoptosis Research, J.C. Reed., Ed., Academic Press, San Diego, CA., 2000; pp: 18-39.

    68 Darzynkiewicz, Z: Cell cycle analysis by flow cytometry. In: Encyclopedia of Life Sciences. Macmillan Reference Ltd, London, 2000 (www.els.net)

    2001

    69. Traganos, F., Juan, G. and Darzynkiewicz, Z.: Cell cycle analysis of drug treated cells. In: Methods in Molecular Biology. Vol. 95, DNA Topoisomerase Protocols. 2001, pp. 229-240

    70. Darzynkiewicz, Z., Juan, G. and Traganos, F.: Assaying drug induced apoptosis. In: Methods in Molecular Biology. Vol 95. DNA Topoisomerase Protocols. N. Osheroff and M.-A Bjornsti Eds. Humana Press., Totowa, N.J., 2001, pp. 241-254.

    71. Juan, G., and Darzynkiewicz, Z.: The detection of apoptosis and DNA replication by differential labeling of DNA strand breaks with fluorochromes of different color. In: Apoptosis and Programmed Cell Death Protocols. Graham Cowling, Ed. Molecular Medicine Series. Humana Press, Totowa, N.J. 2001

    72. Gorczyca, W., Deptala, A., Bedner, E., Li, X., Melamed, M.R., and Darzynkiewicz, Z.: Analysis of human tumors by laser scanning cytometry. In: Meth. Cell Biol., Vol. 64, CYTOMETRY, 3rd Edition. Z. Darzynkiewicz, J.P.Robinson, and H.A.Crissman, Eds. Academic Press, San Diego, CA, 2001; pp. 421-443

    73. Darzynkiewicz, Z., Bedner, E., and Traganos, F.: Difficulties and pitfalls in analysis of apoptosis. In: Meth. Cell Biol. Vol. 63, CYTOMETRY, 3rd Edition. Z.Darzynkiewicz, J.P.Robinson, and H.A.Crissman, Eds. Academic Press, San Diego, CA, 2001; 527-559.

    74. Juan, G., Traganos, F., and Darzynkiewicz, Z.: Methods to identify mitotic cells by flow cytometry. In: Meth. Cell Biol. Vol. 63. CYTOMETRY, 3rd Edition. Z.Darzynkiewicz, J.P.Robinson, and H.A.Crissman, Eds. Academic Press, San Diego, CA, 2001; pp. 343-354.

    75. Darzynkiewicz, Z., Robinson,, J.P., and Crissman, H.A. Preface to 3rd edition. In: Meth. Cell Biol. Vols. 63 & 64, CYTOMETRY, 3rd Edition. Z.Darzynkiewicz, J.P.Robinson, and H.A.Crissman, Eds. Academic Press, San Diego, CA., 2001; pp. xxi-xxiii.

    76. Darzynkiewicz, Z., Li, X., and Bedner, E.: Use of flow- and laser scanning- cytometry in analysis of cell death. In: Meth. Cell Biol. Vol. 66., APOPTOSIS. 2nd Edition,, L. Schwartz and J. Ashwell, Eds., Academic Press, San Diego, CA, 2001; pp. 69-109.

    2002

    77. Grabarek, J., and Darzynkiewicz, Z.: In situ activation of caspases revealed by affinity labeling their enzymatic sites with fluorochrome-labeled inhibitors. In: Caspases. M. Los and H. Walczak, Eds, Landes/ Eurekah.com and Kluwer Academic /Plenum Publishers., New York, NY. 2002; pp 197-209.

    78. Grabarek, J., and Darzynkiewicz, Z.: Section 7. 19. Flow Cytometry of Apoptosis. In: Current Protocols in Cytometry. P. Robinson, Z. Darzynkiewicz, P. Dean, A. Orfao, P. Rabinovitch, C. Stewart, H. Tanke and L. Wheeless, Eds. Current Protocols/Wiley-Liss, New York, N.Y.1998. pp. 7.19.1 - 7.9.33.

    79. Darzynkiewicz, Z. Tribute to Nils R. Ringertz (19932-2002): Personal Memories. Cell Cycle, 1: 232-232, 2002.

    2003

    80. Darzynkiewicz Z, Juan, G., and Traganos, F. Cytometry of cell cycle regulatory proteins. In Progress in Cell Cycle Research Vol. 5. 533-542, 2003 Meijer. L., Jezequel A, Roberge M., Eds. Roscoff, France.

    81. Darzynkiewicz, Z., and Huang, X. Analysis of DNA content by flow cytometry. In Current Protocols in Immunology. R. Coico, Editor. Current Protocols/Wiley-Liss, New York, NY. 2004 pp (in press)

    82. Juan G., and Darzynkiewicz, Z.: Detection of mitotic cells by flow cytometry. In Current Protocols in Cytometry. P. Robinson, Z. Darzynkiewicz, P. Dean, A. Orfao, P. Rabinovitch, C. Stewart, H. Tanke and L. Wheeless, Eds. Current Protocols/Wiley-Liss, New York, N.Y.2004, pp: 7.24.1 - 7.24.6

    2004

    83. Pozarowski , P., and Darzynkiewicz, Z., Analysis of cell cycle by flow cytometry. In: Methods in Molecular Biology, Vol. 281: Checkpoint Controls and Cancer, Vol. 2. Activation and Regulation Protocols. Ed. by : Axel H. Schoenthal, Humana Press, Totowa, NJ. pp. 301-311.

    84. Roederer,, Darzynkiewicz, Z., and Parks, D.R. Guidelines for the presentation of flow cytometric data. In: Methods in Cell Biology, Vol. 75. CYTOMETRY, 4th Edition. Z. Darzynkiewicz, M. Roederer and H.J. Tanke Eds. Elsevier /Academic Press, San Diego, CA (in press).

    85. Darzynkiewicz, Z., Roederer, M., and Tanke H.J. Preface. In: Methods in Cell Biology, Vol. 75. CYTOMETRY, 4th Edition. Z. Darzynkiewicz, M. Roederer and H.J. Tanke Eds. Elsevier /Academic Press, San Diego, CA (in press).

    86. Darzynkiewicz, Z., Huang, X., Okafuji, M., and King, M.A. Cytometric methods to detect apoptosis. In: Methods in Cell Biology, Vol. 75. CYTOMETRY, 4th Edition. Z. Darzynkiewicz, M. Roederer and H.J. Tanke Eds. Elsevier /Academic Press, San Diego, CA (in press).

    87. Blagosklonny, M.,and Darzynkiewicz, Z. Strategies of protection of normal cells during chemo- and radio- therapy based on modulation of cell cycle and apoptotic pathways. In: "Apoptotic pathways as target for novel therapies of cancer and other diseases." edited by M. Los & S.B. Gibson; Kluwer Academic Press, (2004), ISBN: 0-387-23384-9.

    88. Huang, X., Halicka, H.D., and Darzynkiewicz, Z. Detection of histone H2AX phosphorylation on Ser-139 as an indicator of DNA damage (DNA double-strand breaks) In: Current Protocols in Cytometry. P. Robinson, Z. Darzynkiewicz, P. Dean, A. Orfao, P. Rabinovitch, C. Stewart, H. Tanke and L. Wheeless, Eds. Current Protocols/Wiley-Liss, New York, N.Y.2004, in press.

    89. Huang, X., and Darzynkiewicz, Z. Cytometric assessment of histone H2AX phosphorylation, a reporter of DNA damage. In: Methods of Molecular Biology. "DNA Repair Protocols: Eukaryotic systems". D.S. Henderson, Ed. Humana Press., Totowa, N.J. (in press) .

    90. Darzynkiewicz, Z., Pozarowski, P., and Gloria Juan. Cell cycle analysis by flow and laser scanning cytometry. In: Cell Biology. A Laboratory Handbook. Third Edition. Julio E. Celis, Editor. Elsevier/Academic Press, San Diego, CA. (in press)


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